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TEENAGE BASEBALL PITCHERS AT RISK FOR PERMANENT SHOULDER INJURY

Young baseball pitchers who throw more than 100 pitches per week are at risk for a newly identified overuse injury that can impede normal shoulder development and lead to additional problems, including rotator cuff tears, according to a new study published online in the journal Radiology

The injury, termed acromial apophysiolysis by the researchers, is characterized by incomplete fusion and tenderness at the acromion. The acromion, which forms the bone at the top or roof of the shoulder, typically develops from four individual bones into one bone during the teenage years.

"We kept seeing this injury over and over again in young athletes who come to the hospital at the end of the baseball season with shoulder pain and edema at the acromion on MRI, but no other imaging findings," said Johannes B. Roedl, M.D., a radiologist in the musculoskeletal division at Thomas Jefferson University Hospital in Philadelphia.

To investigate the unexplained pain, Dr. Roedl and a team of researchers conducted a retrospective study of 2,372 consecutive patients between the ages of 15 and 25 who underwent magnetic resonance imaging (MRI) for shoulder pain between 1998 and 2012. The majority of the patients, which included both males and females, were baseball pitchers.

"Among high school athletes, pitching is the most common reason for shoulder pain," Dr. Roedl said.

Sixty-one of the patients, (2.6 percent) had pain at the top of the shoulder and an incomplete fusion of the acromion but no other findings. The patients were then age and sex-matched to patients who did not have the condition to form a control group.

Pitching history was available for 106 of the 122 patients included in the study. Through statistical analysis, the researchers found that throwing more than 100 pitches per week was a substantial risk factor for developing acromial apophysiolysis. Among the patients with this overuse injury, 40 percent threw more than 100 pitches per week, compared to 8 percent in the control group.

"We believe that as a result of overuse, edema develops and the acromion bone does not fuse normally," Dr. Roedl explained.

All 61 injured patients took a three-month rest from pitching. One patient underwent surgery while the remaining 60 patients were treated conservatively with non-steroidal pain medication.

Follow-up MRI or X-ray imaging studies conducted a minimum of two years later after the patients turned 25 were available for 29 of the 61 injured patients and for 23 of the 61 controls. Follow-up imaging revealed that 25 of the 29 patients (86 percent) with the overuse injury showed incomplete fusion of the acromion, compared to only 1 of the 23 (4 percent) controls.

"The occurrence of acromial apophysiolysis before the age of 25 was a significant risk factor for bone fusion failure at the acromion and rotator cuff tears after age 25," Dr. Roedl said.

Twenty-one of the 29 patients with the overuse injury continued pitching after the rest period, and all 21 showed incomplete bone fusion at the acromion. Rotator cuff tears were also significantly more common among this group than in the control group (68 percent versus 29 percent, respectively). The severity of the rotator cuff tears was also significantly higher in the overuse injury group compared to the control group.

"This overuse injury can lead to potentially long-term, irreversible consequences including rotator cuff tears later in life," Dr. Roedl said.

Dr. Roedl and his colleagues suggest teenage and young adult pitchers limit the number of pitches thrown in a week to 100. The American Sports Medicine Institute currently recommends that baseball pitchers between 15 and 18 years of age play no more than two games per week with 50 pitches per game.

"Pitching places incredible stress on the shoulder," Dr. Roedl said. "It's important to keep training in the moderate range and not to overdo it."

Dr. Roedl pointed out that many successful professional baseball pitchers played various positions, and even other sports, as young athletes and thereby avoided overuse shoulder injuries.

"More and more kids are entering sports earlier in life and are overtraining," he said. "Baseball players who pitch too much are at risk of developing a stress response and overuse injury to the acromion. It is important to limit stress to the growing bones to allow them to develop normally."

New Drugs To Be Targeted At Pain Receptors Deep In The Nerve Cell

Today's post from sciencedaily.com (see link below) may at first sight seem a little difficult to understand but basically, when the body experiences pain, there are pain receptors on the surface of nerve cells that identify it and transmit the information further and let you feel that pain. If the pain is extreme, sometimes these pain receptors retreat to the nucleus of the cell, as if it's 'safer' there. Pain relieving drugs are designed to block the pain signals in the receptors at the surface of the cell but if the receptors have migrated to the nucleus then the drugs don't have any effect. This knowledge enables researchers to design pain-relieving drugs that can penetrate the nerve cell to the nucleus and thus block the signals from reaching the receptors. They can then 'safely' return to the surface of the cell. At least that's the theory and although it may seem like double-dutch to most of us, sometimes it's interesting to know in which direction the scientists are going.
 

Location may be key to effectively controlling pain
Date:February 3, 2016 Source:McGill University
 
In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain. New research published in Nature Communications indicates that the location of receptors that transmit pain signals is important in how big or small a pain signal will be -- and therefore how effectively drugs can block those signals.

Blocking pain receptors in the nucleus of spinal nerve cells could more effectively control pain than interfering with the same type of receptors located on cell surfaces. The scientists also found that when spinal nerve cells encounter a painful stimulus, some of the receptors will migrate from the cell surface into the nucleus.

A team of researchers led by McGill University's Director of Anesthesia Research Terence Coderre and Karen O'Malley at Washington University in St. Louis, found that rats treated with investigational drugs to block the activity of the receptors in the nucleus soon began behaving in ways that led them to believe the animals had gotten relief from neuropathic pain. According to Prof. Coderre, "drugs that penetrate the spinal nerve cells to block receptors at the nucleus were effective at relieving pain, while those that don't penetrate the nerve cells were not. Rats with nerve injuries had less spontaneous pain and less pain hypersensitivity after blocking receptors at the nucleus, while the pain sensitivity of normal rats was not affected."

Location is key
Scientists have been studying glutamate receptors in the pain pathway for decades. What's new, Coderre explained, is that these most recent experiments -- in cell cultures and rats -- demonstrate that the location of the receptor in the cell has a major effect on the cell's ability to transmit pain signals.

The researchers focused mainly on nerve cells in the spinal cord, an important area for transmitting pain signals coming from all parts of the body.

"We'll now focus our research at determining what events cause the glutamate receptors to migrate to the nucleus, and how to produce drugs that more specifically block glutamate receptors only at the nucleus," added Coderre.

Story Source:

The above post is reprinted from materials provided by McGill University. The original item was written by Cynthia Lee. Note: Materials may be edited for content and length.

Journal Reference:
Kathleen Vincent, Virginia M. Cornea, Yuh-Jiin I. Jong, André Laferrière, Naresh Kumar, Aiste Mickeviciute, Jollee S. T. Fung, Pouya Bandegi, Alfredo Ribeiro-da-Silva, Karen L. O’Malley, Terence J. Coderre. Intracellular mGluR5 plays a critical role in neuropathic pain. Nature Communications, 2016; 7: 10604 DOI: 10.1038/NCOMMS10604

http://www.sciencedaily.com/releases/2016/02/160203111018.htm

Can You Laugh At Your Nerve Pain

Today's post from scopeblog.stanford.edu (see link below) has no direct link to neuropathy but does have a link with living with chronic pain and if you have nerve damage, you know you belong in that family. it's basically an account of how someone compensates their chronic pain with humour and laughter. you need to read the article to see how this works for her but the point on this blog is that we (neuropathy patients) could seriously do with a good laugh now and then, so if you have any funny jokes related to pain, or neuropathy, or any funny stories from the same source, please send them in and share them with the rest of us. Googling 'neuropathy jokes' is a bit like looking for an oasis in the desert but there must be related humour out there somewhere!! Otherwise, this article may just stimulate your laughter buds into action - it's the best form of pain distraction you know.

Laughing through the pain: A comedy writer’s experience with chronic illness
Inspire Contributor on October 13, 2015

We’ve partnered with Inspire, a company that builds and manages online support communities for patients and caregivers, on a patient-focused series here on Scope. Once a month, patients affected by serious and often rare diseases share their unique stories; this month’s column comes from a Los Angeles woman with Ehlers-Danlos Syndrome.

When you fall down at least once a week, you learn to laugh it off. No matter how much it hurts, you laugh because you know it makes other people more comfortable with what’s going on. If they believe you’re all right, your story is a comedy rather than a tragedy. I’m quite sure that this lesson I learned as a child (and have called on hundreds of times since) had a big part in my decision to become a comedy writer and performer, a career I began a decade before I was finally diagnosed with Ehlers-Danlos Syndrome.

Everyone with my rare connective tissue disorder knows the routine of explaining our condition to others. I like to gauge at what point a healthy person’s eyes glaze over and they check out completely; it’s usually around when I get to my issues that are caused by EDS, like arthritis and gastroparesis. After my first few monotonous rundowns of what ails me failed to enthrall anyone, I began weaving elements of humor into my explanations: “I have hip dysplasia, so I can’t be in the Westminster dog show… My joints hyperextend, which is great for sex but terrible for JV soccer… I tore my hamstring in Greece, but it’s not like that’s the worst thing that ever happened there.” Once engaged, people are much more likely to find some aspect of my condition that interests them and ask about that. This type of light interaction is far more comfortable than feeling like I’m teaching an NIH seminar on some disease nobody cares about.

In my experience, the people who really appreciate someone with a sense of humor are those I rely on most: Doctors and nurses. Just after my diagnosis, I was so confused and in so much pain that I was relatively curt with medical professionals. I also thought that if I even smiled, they would think I was faking my illness. But once my symptoms started to improve a bit and I understood more about what was happening, I tried being open and jovial with those who were treating me. The result was great; it should not have come as a surprise that a doctor who likes his patient is more likely to pay attention to her. Regardless of how badly I feel or how much I think something devastating may be happening to my body, I now try my hardest to make whatever dumb jokes I can manage in the hospital or at the doctor’s office. The staff members, many of whom somehow make it through day after day of maudlin events and miserable people, respond quite positively to my Tommy Boy quotes and ridiculous metaphors about how the exam room smells like a robot dog’s pee. (In fact, I would like to think I get better treatment because of David Spade.)

The need to laugh off my issues has become so innate that it is now my first response when I go into shock. My old roommate loves to tell the story of when I stepped onto our back porch and it looked like a sniper hit me: I was down in an instant. She ran out to see what was wrong and found me laughing hysterically, screaming, “I’m fine! Everything’s fine!” When I saw her worried, maternal expression, it made me even more afraid; I knew I had to alleviate her concern for both of our sakes, so I kept up my laughing and made jokes even as the unbelievable pain set in. As it turns out, I had ruptured my Achilles tendon and torn my calf muscle so badly that the orthopedic surgeon said it looked “like pulled pork; like a zipper went down the whole thing from top to bottom.” Looking back, I laughed and joked to make my roommate think everything was fine – the way you would treat a toddler who fell down and looks to you to gauge the severity of his injuries – but really I was the toddler, and making myself laugh got me through it.

I do not know where my life would be without my love of comedy, nor how I would have made it through the ups and downs of Ehlers-Danlos Syndrome. When it comes to relating to people, passing time in the hospital, or just convincing ourselves that there’s a lighter side to almost every situation, the most important part of the human body is the funny bone.

Paula Dixon is a comedy writer and photographer based in Los Angeles. She is a graduate of the USC School of Cinematic Arts and the Spéos Institute of Photography in Paris. She will be returning soon with her humorous podcast The Chronic Life, which covers chronic illness as well as pop culture and personal revelations.

http://scopeblog.stanford.edu/2015/10/13/laughing-through-the-pain-a-comedy-writers-experience-with-chronic-illness/

Sky At Eh Ka A Definition

 
      Imagine. You've come back home after a long day at your office job. You just got off your shift driving a bus or cab for several hours.  You've had an exhausting day lifting heavy loads.

Sharp.  

Burning.  

Radiating.  

Constant pain starts gradually around your lower back and then travels down to your buttocks, thighs, and leg.  Sciatica can happen to a number of people who are otherwise healthy but is most common in their 50's.  The name comes from the nerve which it affects - the sciatic nerve.

The sciatic nerve originates low in the spinal column and extends down each leg.

Nerves are bundles of neurons (special cells in the body for relaying messages) that connect the brain and spine to everything and anything in the body.  In this case we're talking about the long, large nerve that's responsible for relaying information from the lower back down the back of your legs to the tips of your toes.  There's a matching pair in your body, one going down each leg from the spine.  As it travels down the back of your leg it branches off into individual nerves to cover the thigh, calf, foot, and toes.  

When this nerve gets irritated or inflamed, it creates pain.  Sciatica itself is not a disease but a distinctive symptom that is the result of several medical conditions.  Most often it is due to a structural change in the spine or when a muscle deep in the buttocks called the piriformis squeezes down on the nerve.  It may start out as a mild ache and build up to a sharp, burning pain over time.

It can be aggravated by long periods of sitting or standing, physical activity, and/or coughing and sneezing.  In its early stages it can be managed conservatively with simple exercises by a chiropractor and heat/ice therapy.  If the pain worsens or becomes chronic more aggressive treatments such as pain killers and surgery may be considered.

References

Diseases & Conditions: What is Sciatica? (2014, September 8). Retrieved April 5, 2015, from [link]
H. Hochshuler MD, S. (2012, February 12). What You Need to Know About Sciatica. Retrieved April 5, 2015, from  Sciatica. (2012, September 19). Retrieved April 5, 2015, from [link]
Sciatica: MedlinePlus Medical Encyclopedia. (2014, September 8). Retrieved April 5, 2015, from [link]

Treating sciatica pain at home

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The Spectrum and the Spiral and a FREE sneak peek at the Ladys Slipper home study content!

Actually I think one of the best preventative medicines for the immune system is connecting to the rhythms of the seasons. I felt fall the morning of August 1. There is a deeper calendar in our bodies that lets us know what we need to do to keep ourselves strong and resilient. This is the learning we do as a tribe of re-connectors; plant medicine people, real food makers, and self-employed artists. We give ourselves the room to be gut-led, weather-led, cycle led. 
In this context, herbs seldom fail to work with us.
~~~~~~~~~~~

Greetings and happy Autumn, friends!

----------

Here, the air in the morning calls the mist down from the mountains, the dew sparkles across the knotweed, and the lilting sun is gentle only 'till noon. 

Then it's hot for a fleeting couple of hours; just the window of opportunity needed to collect the wild plants I need for medicine making. 

I've already begun harvesting some roots, and soon will be sassafras, autumn olive and rose hips. 

~~

Are you feeling the season? What does it smell like, taste like, sound like? Our senses are reliable informants. 

Slippery Evening Primrose Roots

Most of my work in life is based on two philosophies. 
The Spectrum, and the Spiral. 

This is, like the doshas and the humors and the 5 element theory, a general direction of understanding in which I can draw insight from. 

The tendency of the spectrum is a kind of holistic polarity, whereby seemingly opposing energies can be harmonized to create homeostasis.

A simple example might be the idea of spicy ginger helping a cold stagnant cough, or the dancer's attitude: where each of the far reaching points of the body are in direct relationship with the center, and both must be equally tended in order to achieve a steady balance and moment of beauty. 

The tendency of the spiral represents all of natural law within the elusive span of time. It's sort of a quantum knowing that we repeat patterns of growth that are similar or same, yet in the moment of time it occurs, it is completely unique; never to be expressed that exact same way again.

The spiral occurs in our lives when we recognize an experience, or a season, a taste, or a feeling. It occurs in our body as it continually regenerates, and it occurs in our perspectives and outlooks on life as we mature and ripen. We walk the spiral and expand each time. 

I say all this not just to evangelize my new-agey ideas, but to offer a way of walking through life with poetic stride, as each challenge comes our way and asks us to become more of ourselves. 

This is the context in which I offer the herbal lifeways taught and activated within the Lady's Slipper Ring Membership. 

Herbs sometimes work on their own. Personal growth sometimes works on its own. However, as we see in the spectrum of polarities, Internal and External work can transform and empower us most deeply and effectively when they are both engaged simultaneously.

Why enroll in the Lady's Slipper Ring? Well, really that is an answer only you can determine. 

If there is even a small voice inside you, calling you to become more deeply connected to your senses, your intuition, your body's innate wisdom, then I sincerely invite you along this delicious journey. 

Here is an offering to you - an excerpt from the home study components!

Remember, though, that this is out of context of the membership spiral, and it will be a spoiler for that month! 

CLICK HERE for the Moon Seven Invitations

and CLICK HERE for the Moon Seven Potions

Need another little incentive?

~~Pay in full members get one month FREE

~~Enrollments before October 14 receive a free welcome gift! 

~~All completing members receive a handmade Lady's Slipper ceramic pendent as a completion gift in the last month. 

~~Free Issues of the famed Herbal Roots Zine, to enrich your home apothecary and plant knowledge

~~But of course, YOU and your richer, more empowered and luscious self will be the biggest reward of all. 

Welcome! 

With Love,

Ananda

Ectopic Pregnancy Symptoms At 6 Weeks

Ectopic Pregnancy Symptoms And Signs

One in every 60 pregnancies is ectopic, a word that means "out of place." In an ectopic pregnancy, a fertilized egg attaches or implants itself somewhere other .Learning about ectopic pregnancy: What is an ectopic pregnancy? What are the symptoms? What increases my risk of having an ectopic pregnancy? What are the dangers of .Know what to expect in week 6 pregnancy. Learn how your baby is growing in 6th week of pregnancy. Get more information on 6 weeks pregnant symptoms..An ectopic pregnancy happens when an embryo develops outside the womb uterus . Discover why it happens, how common it is, and the signs and symptoms of ectopic .What is an ectopic pregnancy? Ectopic means "in the wrong place", and is a pregnancy that develops outside of your uterus womb . More than 95 per cent of ectopic .At 6 weeks pregnant, learn about your pregnancy symptoms, when the heartbeat can be seen with ultrasound, healthy nutrition and severe morning sickness..Risk factors for ectopic pregnancy . Previous ectopic pregnancy is a major risk factor for having another tubal pregnancy. Details on pregnancy after ectopic pregnancy.Ectopic pregnancy, also known as eccyesis or tubal pregnancy, is a complication of pregnancy in which the embryo attaches outside the uterus. Signs and symptoms .Three classic signs and symptoms of an ectopic pregnancy What are other signs and symptoms of an ectopic pregnancy?.An ectopic pregnancy occurs when an embryo implants somewhere other than the uterus, such as in one of the fallopian tubes. Learn more from WebMD about the symptoms .

Ectopic Pregnancy Symptoms And Signs

Fallopian Tube Ectopic Pregnancy

The most prominent ectopic pregnancy symptoms will be at 6 weeks of the pregnancy cause ectopic pregnancies, such ectopic pregnancy symptoms will be at 6 .Learning about ectopic pregnancy: What is an ectopic pregnancy? What are the symptoms? What increases my risk of having an ectopic pregnancy? What are the .An ectopic pregnancy may be found at any time between five weeks and 14 weeks of pregnancy ectopic pregnancy symptoms? Ectopic Pregnancy Trust. . Dr. Champine on signs of ectopic pregnancy at 6 weeks: Signs of twin pregnancy at 6 weeks; Symptoms of ectopic pregnancy at 4 weeks;.Patient Comments: Ectopic Pregnancy - Symptoms. Pregnancy Week By Week, Trimesters Signs and symptoms of pregnancy vary by stage trimester .. Ectopic pregnancy | Mom Answers. EXPERT Yes i was told i had miscarried at 6 weeks but after a further 2 weeks of blood I had no symptoms or . The dr said this could mean a possible ectopic pregnancy, pregnancy have no symptoms at 6 1/2 weeks? Can an ectopic pregnancy have no symptoms .Probably the most dangerous cause for bleeding during the 1st trimester is an ectopic pregnancy. Ectopic pregnancy occurs when your fertilized egg implants somewhere .An ectopic pregnancy occurs when an embryo implants somewhere other than the uterus, such as in one of the fallopian tubes. Learn more from WebMD about the symptoms .Symptoms of ectopic pregnancy Written by Jason King, August 10th, 2016. and symptoms may occur from as early as 4 weeks pregnant and up to 12 weeks or .

SIZE AT BIRTH AFFECTS MENTAL DISORDER RISK

New research from the Copenhagen Centre for Social Evolution and Yale University offers compelling support for the general evolutionary theory that birth weight and -length can partially predict the likelihood of being diagnosed with mental health disorders such as autism and schizophrenia later in life. The study analyzed medical records of 1.75 million Danish births, and subsequent hospital diagnoses for up to 30 years, and adjusted for almost all other known risk factors. The study is published in theProceedings of the Royal Society, London B.

The number of people diagnosed with mental health disorders is on the rise in most affluent countries, but we do not yet have a comprehensive understanding of the factors that make people vulnerable to these disorders.

A new analysis of the extensive Danish public health database suggests that part of the answer may reside in genetic imprints established at conception that influence both size at birth and mental health during childhood and early adolescence.

The study tests predictions of the evolutionary theory of genomic imprinting -- the idea that during fetal development some genes inherited from the mother are expressed differently to those inherited from the father. The potential consequence of this asymmetry is that maternal and paternal genes in a fetus will not cooperate fully during this period, even though they subsequently have shared interests due to their lifetime commitment to the same body.

Opposite forces balance each other

The reason for the conflict is that some of the genes known to be expressed in the placenta and the brain carry imprints that affect resource provisioning of the unborn child. When such genes come from the father, they favor investment of more of the mother's resources in the developing fetus, whereas the maternally-imprinted genes will normally compensate for such paternally-influenced manipulative effects to lessen the drain on maternal resources. These opposite forces balance each other in most pregnancies, with the result that most children are born with close to average length and weight and with a high likelihood of balanced mental health development.

Small deviations may well be favorable in human populations, when somewhat heavier babies are more likely to develop abstract talents and somewhat lighter babies above average social talents, for instance. However, this incurs the risk of increasing the frequency of autistic- and schizophrenic-spectrum disorders in the rare cases where imprinting imbalances are larger. The theory may explain why natural selection has not removed this portion of the burden of mental disease from our ancestors.

The new study tests these predictions^, and its results are remarkably consistent. They show that the change to the risk of developing mental disorders when born smaller or larger than average are relatively small, but very consistent, clearly diametrical, and part of the single continuum that the theory predicts.

"When we started this large scale analysis four years ago, we hoped to find evidence that genetic imprinting happens, but we did not expect that the results would match the predictions as consistently as we found," explains Professor Jacobus Boomsma, Director of the Centre for Social Evolution, University of Copenhagen, who coordinated the work.

Boomsma adds: "Our study confirms that larger babies have a higher risk for incurring autism-spectrum diagnoses later in life and lower risk for schizophrenia-spectrum disorders. For example, Danish newborns are on average 52 cm long and being born at 54 cm increases the autism risk by 20%. However, these are relative risks and these disorders remain rare: in this example the absolute risk increases from 0.65% to 0.78%. Risk patterns are opposite in smaller newborns, who have higher risks for schizophrenia and lower risks for autism. Only for the smallest, prematurely-born babies does this diametric pattern disappear, because they have elevated risks for almost all disease categories."

Evolutionary conflicts

Boomsma also underlines that focused genomic studies will be needed to find out which genes are involved and how they affect brain function: "Our Centre's main objective is to develop and test evolutionary theory about the ways in which gene-level conflicts can corrupt even the most sophisticated forms of naturally evolved cooperation. It is no surprise that humans are vulnerable to such deep evolutionary conflicts, as are other mammals, and it is both useful and interesting to be aware of this part of our biological heritage," says Professor Boomsma.

Pregnancy At 6 Weeks

Cleveland Clinic Internships

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Pregnancy Boudoir Shoot Ideas

Christmas Pregnancy Announcement

Video embedded Your baby's nose, mouth, and ears are beginning to take shape at 6 weeks pregnant. You may be having morning sickness and spotting..At 6 weeks pregnant, learn about your pregnancy symptoms, when the heartbeat can be seen with ultrasound, healthy nutrition and severe morning sickness..At 6 weeks pregnant, your baby is the size of a sweet pea! Monitor your pregnancy week-by-week on WhatToExpect.com and download our app..A guide on pregnancy at 6 weeks with information on what to expect, baby development, and symptoms. Learn about being 6 weeks pregnant..WebMD tells you how you'll be feeling in weeks 5-8 of your pregnancy, along with how your baby is developing in the womb..6 weeks pregnant - Get information on fetal growth and development, baby's size and common symptoms when you're 6 weeks pregnant. Get tips, advice and answers to .What's happening in week six of your pregnancy? Your baby's heart is the size of a poppy seed and hormones have kicked. Find out more about week six..Pregnancy Week 6. Discover how your baby is developing in week six. Now is the time to start deciding where you want to deliver your baby and who will be a part of .6 Weeks Pregnant. Here's what's happening during Week 6 of your pregnancy. Facebook Pinterest Google Plus Text Email. Week Week 5 Week 6 Week 7 See All. .6 weeks pregnant: here's what you need to know about how your baby's growing and looking after your health in pregnancy. - BabyCentre.